TotalSeq™-B0437 anti-mouse/human CD207 (Langerin) Antibody, CD207, 4C7,BioLegend,144213
Host
Mouse
Reactivity
Mouse, Human
Application
PG -Quality tested
Platform ID
BAB311185026
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-B0437 anti-mouse/human CD207 (Langerin) Antibody, CD207, 4C7
Cat. No.144213
HostMouse
RRIDAB_2876492 (BioLegend Cat. No. 144213)
IsotypeMouse IgG2a, κ
ReactivityMouse, Human
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone Number4C7
Concentration0.5 mg/mL
TargetCD207
ImmunogenLangerin extracellular domain-Fc fusion protein
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD207, also known as langerin, is a 40 kD single-pass type II transmembrane protein, member of the C-type lectin family. CD207 is expressed on the cell surface and Birbeck granules (BGs) of Langerhans cells, and subsets of thymic and splenic dendritic cells. Its ligands are mannose,n-acetylglucosamine, fucose, and sulfated glycans. Langerin is involved in the antigen processing pathway through capture and internalization of its ligands.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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