TotalSeq™-B0565 anti-mouse MERTK (Mer) Antibody, MERTK (Mer), 2B10C42,BioLegend,151525

Host

Rat

Reactivity

Mouse

Application

PG -Quality tested

Platform ID

BAB106826843

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B0565 anti-mouse MERTK (Mer) Antibody, MERTK (Mer), 2B10C42
Cat. No.151525
HostRat
RRIDAB_2876510 (BioLegend Cat. No. 151525)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone Number2B10C42
Concentration0.5 mg/mL
TargetMERTK
ImmunogenMouse MERTK extracellular domain
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

MerTK (Mer) is a member of the TAM (TYRO3/AXL/MerTK) family. It is a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. MerTK is mainly expressed by macrophages, monocytes, and dendritic cells. Its ligands are LGALS3, TUB, TULP1, and GAS6. MerTK is involved in the regulation of TLR signaling, efferocytosis, phagocytosis, cell survival, macrophage migration, and the inhibition of inflammation.

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