TotalSeq™-B0565 anti-mouse MERTK (Mer) Antibody, MERTK (Mer), 2B10C42,BioLegend,151525
Host
Rat
Reactivity
Mouse
Application
PG -Quality tested
Platform ID
BAB106826843

BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-B0565 anti-mouse MERTK (Mer) Antibody, MERTK (Mer), 2B10C42
Cat. No.151525
HostRat
RRIDAB_2876510 (BioLegend Cat. No. 151525)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone Number2B10C42
Concentration0.5 mg/mL
TargetMERTK
ImmunogenMouse MERTK extracellular domain
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
MerTK (Mer) is a member of the TAM (TYRO3/AXL/MerTK) family. It is a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. MerTK is mainly expressed by macrophages, monocytes, and dendritic cells. Its ligands are LGALS3, TUB, TULP1, and GAS6. MerTK is involved in the regulation of TLR signaling, efferocytosis, phagocytosis, cell survival, macrophage migration, and the inhibition of inflammation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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