TotalSeq™-B0825 anti-mouse CD371 (CLEC12A) Antibody, CD371, 5D3/CLEC12A,BioLegend,143411

Host

Rat

Reactivity

Mouse

Application

PG - Quality tested

Platform ID

BAB816732362

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B0825 anti-mouse CD371 (CLEC12A) Antibody, CD371, 5D3/CLEC12A
Cat. No.143411
HostRat
RRIDAB_2888721 (BioLegend Cat. No. 143411)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone Number5D3/CLEC12A
Concentration0.5 mg/mL
TargetCD371
ImmunogenCHO expressing mouse CLEC12A
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family.  Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases. Mouse CLEC12A is expressed on CD8+dendritic cells (DCs), a proportion of CD8-dendritc cells, plasmacytoid DCs, monoctyes, macrophages, granulocytes, and B cells.

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