TotalSeq™-B0887 anti-mouse CD339 (Jagged 1) Antibody, CD339, HMJ1-29,BioLegend,130917

Additional reported applications (for the relevant formats) include:in vivoblocking of Jagged 1 in EAE1and immunohistochemical staining of frozen spleen sections2.

Host

Armenian Hamster

Reactivity

Mouse

Application

PG - Quality tested

Platform ID

BAB548604803

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B0887 anti-mouse CD339 (Jagged 1) Antibody, CD339, HMJ1-29
Cat. No.130917
HostArmenian Hamster
RRIDAB_2890687 (BioLegend Cat. No. 130917)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberHMJ1-29
Concentration0.5 mg/mL
TargetCD339
ImmunogenMurine Jagged 1-Fc fusion protein
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD339, also known as Jagged 1, is a 135 kD type 1 transmembrane protein, with one DSL (Delta, Serrate, LagZ) domain, fifteen EGF-like domains, and one cysteine-rich region. Jagged 1 is expressed by many cell types including macrophages, subsets of dendritic cells, astrocytes, stromal, and epithelial cells. CD339 regulates cell fate decisions in various tissues, and has an important role in neurogenesis and development of the cardiovascular system. Studies suggest Jagged 1 is involved in Th2 polarization and Treg induction.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.