TotalSeq™-B1024 anti-human CD120b Antibody, CD120b, 3G7A02,BioLegend,358421
Host
Rat
Reactivity
Human
Application
PG – Quality tested
Platform ID
BAB294870332
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameTotalSeq™-B1024 anti-human CD120b Antibody, CD120b, 3G7A02
Cat. No.358421
HostRat
RRIDAB_2910403 (BioLegend Cat. No. 358421)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationPG – Quality tested
ClonalityMonoclonal
Clone Number3G7A02
Concentration0.5 mg/mL
TargetCD120b
ImmunogenPartial CD120b recombinant protein expressed in 293E cells (22-211aa).
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD120b, also known as TNFRII or TNFRSF1B, belongs to the TNF receptor superfamily and can interact with ligands TNF-α and TNF-β (also known as LT-α). It is a 75 kD type I transmembrane protein expressed on lymphocytes, monocytes, and granulocytes. When present in a heterocomplex with CD120a, it induces the recruitment of anti-apoptotic molecules, c-IAP1 and c-IAP2 that possess E3 ubiquitin ligase activity. Mutations in CD120b are associated with TNF-associated periodic syndrome (TRAPS) or periodic fever syndrome.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.