TotalSeq™-B1051 anti-human Podocalyxin Antibody, Podocalyxin, mAb 84,BioLegend,374307

Additional reported applications (for relevant formats) include: WB, IP, cytotoxicity. The LEAF purified format is recommended for cytotoxicity assays.

Host

Mouse

Reactivity

Human

Application

PG - Quality tested

Platform ID

BAB374954402

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B1051 anti-human Podocalyxin Antibody, Podocalyxin, mAb 84
Cat. No.374307
HostMouse
RRIDAB_2892457 (BioLegend Cat. No. 374307)
IsotypeMouse IgM, κ
ReactivityHuman
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumbermAb 84
Concentration0.5 mg/mL
TargetPodocalyxin
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Podocalyxin-like protein-1 (also known as PODXL, GP200, PCLP1 and GCTM2) is expressed on the surface of undifferentiated human ES cells and glomerular podocytes. PODXL was originally described as the main sialoprotein expressed by glomerular epithelial cells. Recently PODXL been associated with several forms of cancer and is being targeted as a possible therapeutic. Clone mAb 84 is reported to recognize and have cytotoxic affects against undifferentiated human ES cells.

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