TotalSeq™-B1064 anti-mouse/rat CD81 Antibody, CD81, Eat-2,BioLegend,104919
The Eat-2 antibody reacts with mouse and rat CD81. Additional reported applications (for the relevant formats) include: immunoprecipitation1,2, Western blotting1,2, induction of homotypic adhesion of B lymphocytes1, stimulation of B cells undergo early apoptotic events1, and promotion of T cell motility2.
Host
Armenian Hamster
Reactivity
Mouse, Rat
Application
PG - Quality tested
Platform ID
BAB721155732
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-B1064 anti-mouse/rat CD81 Antibody, CD81, Eat-2
Cat. No.104919
HostArmenian Hamster
RRIDAB_3083101 (BioLegend Cat. No. 104919)
IsotypeArmenian Hamster IgG1, κ
ReactivityMouse, Rat
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberEat-2
Concentration0.5 mg/mL
TargetCD81
ImmunogenCD81+ mouse B lymphoma 38C13
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1. CD81 is expressed on T and B cells, NK cells, dendritic cells, thymocytes, endothelial cells, and fibroblasts. CD81 induces B cell adhesion via the VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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