TotalSeq™-B1099 anti-human Granzyme A Antibody, Granzyme A, CB9,BioLegend,507223

Additional reported applications (for the relevant formats) include: immunohistochemical staining3of formalin-fixed paraffin-embedded tissue sections, and immunoprecipitation2.

Host

Mouse

Reactivity

Human

Application

ICPG - Quality tested

Platform ID

BAB777340015

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B1099 anti-human Granzyme A Antibody, Granzyme A, CB9
Cat. No.507223
HostMouse
RRIDAB_3083207 (BioLegend Cat. No. 507223)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationICPG - Quality tested
ClonalityMonoclonal
Clone NumberCB9
Concentration0.5 mg/mL
TargetGranzyme A
ImmunogenPurified human Granzyme A
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Granzyme A is a 28 kD disulfide-linked homodimeric protein and the most abundant of the proteases occurring in CTL granules. It is homologous to other serine esterases, including other granyzmes, mast cell proteases, and neutrophil cathepsins. Granzyme B is thought to be a rapidly-acting apoptotic enzyme, while Granzyme A is slow acting. The CB9 monoclonal antibody recognizes human Granzyme A and has been shown to be useful for flow cytometry, immunoprecipitation, and immunohistochemistry (paraffin-embedded sections).

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