TotalSeq™-B1281 anti-mouse CD16 Antibody, CD16, S17014E,BioLegend,158025

Anti-mouse CD16/32 clones 93 and 2.4G2 both block clone S17014E staining.

Host

Rat

Reactivity

Mouse

Application

PG - Quality tested

Platform ID

BAB380740359

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B1281 anti-mouse CD16 Antibody, CD16, S17014E
Cat. No.158025
HostRat
RRIDAB_3068299 (BioLegend Cat. No. 158025)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberS17014E
Concentration0.5 mg/mL
TargetCD16
ImmunogenMouse CD16 - transfected cells
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD16 also know as Fcgr3 is a 50-65 kD type I transmembrane protein, member of the Fc gamma receptor family and  Ig superfamily. CD16  is expressed  on most myeloid cells including monocytes, macrophages, dendritic cells, and is also expressed by NK cells and NKT cells. CD16 is involved in cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC); its ligands are IgG1, IgG2a and IgG2b.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.