TotalSeq™-C0057 anti-human β2-microglobulin Antibody, β2-microglobulin, 2M2,BioLegend,316323
Additional reported applications (for the relevant formats) include: Western blotting, and ELISA.
Host
Mouse
Reactivity
Human
Application
PG -Quality tested
Platform ID
BAB400830711
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C0057 anti-human β2-microglobulin Antibody, β2-microglobulin, 2M2
Cat. No.316323
HostMouse
RRIDAB_2800837 (BioLegend Cat. No. 316323)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone Number2M2
Concentration0.5 mg/ml
Targetbeta2-microglobulin
ImmunogenPurified human β2-microglobulin
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+T cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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