TotalSeq™-C0066 anti-human CD7 Antibody, CD7, CD7-6B7,BioLegend,343127
Additional reported (for the relevant formats) applications include proteogenomics2.
Host
Mouse
Reactivity
Human
Application
PG -Quality tested
Platform ID
BAB466033192
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C0066 anti-human CD7 Antibody, CD7, CD7-6B7
Cat. No.343127
HostMouse
RRIDAB_2800914 (BioLegend Cat. No. 343127)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberCD7-6B7
Concentration0.5 mg/ml
TargetCD7
ImmunogenKG1a cell line
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
Regulatory StatusResearch Use Only
Scientific Background
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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