TotalSeq™-C0370 anti-human CD303 (BDCA-2) Antibody, CD303, 201A,BioLegend,354241

Host

Mouse

Reactivity

Human

Application

PG -Quality tested

Platform ID

BAB609697993

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameTotalSeq™-C0370 anti-human CD303 (BDCA-2) Antibody, CD303, 201A
Cat. No.354241
HostMouse
RRIDAB_2814295 (BioLegend Cat. No. 354241)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone Number201A
Concentration0.5 mg/ml
TargetCD303
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and TLR-9 induced pDCs maturation.

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