TotalSeq™-C0376 anti-mouse CD195 (CCR5) Antibody, CD195, HM-CCR5,BioLegend,107023
CCR5 is expressed at low density on activated cells. For successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 107006) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 107004) or biotinylated anti-Armenian hamster IgG (Cat. No. 405501) second step, followed by SAv-PE (Cat. No. 405204)).
Host
Armenian Hamster
Reactivity
Mouse
Application
PG - Quality tested
Platform ID
BAB922592789
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C0376 anti-mouse CD195 (CCR5) Antibody, CD195, HM-CCR5
Cat. No.107023
HostArmenian Hamster
RRIDAB_2941378 (BioLegend Cat. No. 107023)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberHM-CCR5
Concentration0.5 mg/mL
TargetCD195
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD195 is a 45 kD chemokine receptor also known as CCR5. CD195 is a seven transmembrane-spanning G protein-associated molecule expressed on macrophages, a T cell subset, and in the heart, liver, and spleen. CD195 regulates lymphocyte chemotaxis and transendothelial migration during inflammatory processes. CD195 interacts with several ligands including RANTES, MCP-1, MIP-1α, and MIP-1β.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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