TotalSeq™-C0443 anti-mouse CD41 Antibody, CD41, MWReg30,BioLegend,133943
Additional reported applications (for the relevant formats) include: depletion of platelets and functional assayin vivo.4,7The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended forin vivostudies (Cat. No. 133939).
Host
Rat
Reactivity
Mouse
Application
PG -Quality tested
Platform ID
BAB133025526
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C0443 anti-mouse CD41 Antibody, CD41, MWReg30
Cat. No.133943
HostRat
RRIDAB_2876469 (BioLegend Cat. No. 133943)
IsotypeRat IgG1, κ
ReactivityMouse
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberMWReg30
Concentration0.5 mg/mL
TargetCD41
ImmunogenMouse platelets
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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