TotalSeq™-C0823 anti-mouse CD34 Antibody, CD34, SA376A4,BioLegend,152211

This antibody (clone SA376A4) is useful for staining mouse CD34+hematopoietic stem cell but it does not stain NIH-3T3 cells and the staining of Bend.3 cells is dimmer compared to other mouse CD34 antibodies, probably due to this antibody recognizes a different epitope than the other monoclonal antibodies.

Host

Rat

Reactivity

Mouse

Application

PG -Quality tested

Platform ID

BAB889786015

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameTotalSeq™-C0823 anti-mouse CD34 Antibody, CD34, SA376A4
Cat. No.152211
HostRat
RRIDAB_2832536 (BioLegend Cat. No. 152211)
IsotypeRat IgG2a, λ
ReactivityMouse
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberSA376A4
Concentration0.5 mg/mL
TargetCD34
ImmunogenMouse CD34 transfected cells.
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD34, also known as gp105-120, is a highly glycosylated type I monomeric sialomucin-like glycophophoprotein with an approximate molecular weight of 105-120 kD, with two generated by alternative splicing. CD34 is expressed on hematopoietic progenitors, endothelial cells, brain, and testis. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands, and mediates the attachment of stem cells to the extracellular matrix or stromal cells. CD34 is phosphorylated on serine residues by PKC.

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