TotalSeq™-C0840 anti-mouse Ly49G Antibody, Ly49G, AT8,BioLegend,137405

Host

Mouse

Reactivity

Mouse

Application

PG - Quality tested

Platform ID

BAB080950534

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameTotalSeq™-C0840 anti-mouse Ly49G Antibody, Ly49G, AT8
Cat. No.137405
HostMouse
RRIDAB_2876478 (BioLegend Cat. No. 137405)
IsotypeMouse IgG2a, κ
ReactivityMouse
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberAT8
Concentration0.5 mg/mL
TargetLy49G
ImmunogenIL-2-activated 129/J NK cells
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Ly49G is a type II transmembrane protein belonging to the family of Ly49 proteins, each having specificity for a small repertoire of MHC I alleles that are generally recognized in a peptide-independent manner.   The Ly49 family of MHC class I receptors shows a high degree of variability between mouse strains.  It is expressed on a subset of NK cells and some NKT cell lines.  The AT8 antibody reacts with the Ly49G receptor from BALB/c, 129/J, 129Sv/J, SJL, FVB/N, A/J, C3H/HeJ, C3H/HeNCr, CBA/J, and CBA/NCr mice.

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