TotalSeq™-C0850 anti-mouse CD49a Antibody, CD49a, HMα1,BioLegend,142615
Additional reported applications (for the relevant format) include: inhibition of cell adhesion and cytokine production1,2.
Host
Armenian Hamster
Reactivity
Mouse
Application
PG -Quality tested
Platform ID
BAB298879671
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C0850 anti-mouse CD49a Antibody, CD49a, HMα1
Cat. No.142615
HostArmenian Hamster
RRIDAB_2832511 (BioLegend Cat. No. 142615)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberHMα1
Concentration0.5 mg/mL
TargetCD49a
ImmunogenMouse Neuroblastoma Cell Line C1300
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD49a is a 1179 aa, type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α chain, or integrin α1. It associates antibody v042010 with CD29 (β1 integrin) to form the VLA-1 complex, a collagen IV and alminin-1 receptor that is expressed on activated T cells, smooth muscle cells, endothelial cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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