TotalSeq™-C0852 anti-mouse CD226 (DNAM-1) Antibody, CD226, 10E5,BioLegend,128825
Host
Rat
Reactivity
Mouse
Application
PG - Quality tested
Platform ID
BAB600402457
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C0852 anti-mouse CD226 (DNAM-1) Antibody, CD226, 10E5
Cat. No.128825
HostRat
RRIDAB_2890686 (BioLegend Cat. No. 128825)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone Number1000000
Concentration0.5 mg/mL
TargetCD226
ImmunogenTh1 polarized T cell clones
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD226 (DNAM-1) is constitutively expressed on native CD8+cells and on CD4+T cells, macrophages and NK cells.This antibody (10E5) was reported to bind about 40% of inactivated CD4+cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic encephalitis) mediated by Th1 cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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