TotalSeq™-C0879 anti-mouse IL-21R Antibody, IL-21R, 4A9,BioLegend,131911

Host

Rat

Reactivity

Mouse

Application

PG -Quality tested

Platform ID

BAB122641777

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameTotalSeq™-C0879 anti-mouse IL-21R Antibody, IL-21R, 4A9
Cat. No.131911
HostRat
RRIDAB_2876466 (BioLegend Cat. No. 131911)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone Number4A9
Concentration0.5 mg/mL
TargetIL-21R
ImmunogenRat YB2/0 hybridoma transfectant cell line expressing truncated IL-21R
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The IL-21R is a member of the cytokine receptor family that closely resembles IL-2R beta and IL-4R alpha. IL-21R is expressed by all mature lymphocytes and up-regulated after B and/or T cell activation, with the highest expression by activated B cells. A functional IL-21R consists of the IL-21R subunit and the commone gamma-chaiin. Upon binding to IL-21, it activates Jak-1, Jak-3, STAT1, STAT3 and STAT 5 transduction pathway.

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