TotalSeq™-C1018 anti-human HLA-DR, DP, DQ Antibody, HLA-DR, DP, DQ, Tü39,BioLegend,361725
Tü39 has been reported to react with a shared epitope of HLA-DR, HLA-DP, and HLA-DQ.Additional reported applications (of relevant formats) include immunoprecipitation6,in vitroblocking of MLR5, and suppressor cell generation4. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (contact our custom solutions team).
Host
Mouse
Reactivity
Human
Application
PG - Quality tested
Platform ID
BAB410737218
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C1018 anti-human HLA-DR, DP, DQ Antibody, HLA-DR, DP, DQ, Tü39
Cat. No.361725
HostMouse
RRIDAB_3097473 (BioLegend Cat. No. 361725)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberTü39
Concentration0.5 mg/mL
TargetHLA-DR DP DQ
ImmunogenHuman PBL
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
HLA-DR, HLA-DP, and HLA-DQ are heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Variations in the HLA gene expression are crucial to graft survival.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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