TotalSeq™-C1038 anti-human C3AR Antibody,C3aR, hC3aRZ8,BioLegend,345811
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections2.
Host
Mouse
Reactivity
Human
Application
PG - Quality tested
Platform ID
BAB104339302
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C1038 anti-human C3AR Antibody,C3aR, hC3aRZ8
Cat. No.345811
HostMouse
RRIDAB_2927918 (BioLegend Cat. No. 345811)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberhC3aRZ8
Concentration0.5 mg/mL
TargetC3AR
ImmunogenhC3aR transfected cells
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
C3AR is a single chain protein of 482 aa, with seven membrane-spanning regions and a molecular weight of 54 Kd. C3AR is expressed by neutrophils, eosinophils, mast cells, monocytes, dendritic cells and there are reports of C3AR expression in non-immune cells such as hematopoietic and mesenchymal stem cells, epithelial and endothelial cells. C3AR is coupled to heterotrimeric G proteins and after C3a binding, the signal transduced, results in chemotaxis, granule enzyme release and superoxide anion production.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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