TotalSeq™-C1057 anti-human DR3 (TRAMP) Antibody, DR3, JD3,BioLegend,307107
Additional reported applications (for the relevant formats) include: The JD3 antibody is useful for immunofluorescent staining and flow cytometric analysis of DR3/TRAMP receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307106) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 307104) or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).
Host
Mouse
Reactivity
Human
Application
PG -Quality tested
Platform ID
BAB177515425

BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C1057 anti-human DR3 (TRAMP) Antibody, DR3, JD3
Cat. No.307107
HostMouse
RRIDAB_2832605 (BioLegend Cat. No. 307107)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberJD3
Concentration0.5 mg/mL
TargetDR3
Immunogenhuman DR3-Ig fusion protein
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
DR3 is also known as TNFRSF25, Apo-3, WSL-1, TRAMP, LARD, DDR3, and TR3. It is a member of the TNF receptor family expressed at low level by monocytes and granulocytes. Interaction of DR3 with its ligand (TWEAK), activates the NF-κB pathway and induces apoptosis.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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