TotalSeq™-C1276 anti-human CD263 (DcR1, TRAIL-R3) Antibody, CD263, DJR3,BioLegend,307011
Additional reported applications (for the relevant formats) include: The DJR3 antibody is useful for immunofluorescent staining and flow cytometric analysis of DcR1/TRAIL-R3 receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307006) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 307004) or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).
Host
Mouse
Reactivity
Human
Application
PG - Quality tested
Platform ID
BAB468831848
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C1276 anti-human CD263 (DcR1, TRAIL-R3) Antibody, CD263, DJR3
Cat. No.307011
HostMouse
RRIDAB_3720632 (BioLegend Cat. No. 307011)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberDJR3
Concentration0.5 mg/mL
TargetCD263
ImmunogenExtracellular domain of DcR1-human IgG1 Fc fusion protein
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
DcR1 is a 65 kD GPI-anchored member of the TNFR superfamily (TNFRSF10C) also known as TRAIL-R3, TRID, CD263, and LIT. Although not expressed by most tumors, DcR1 is expressed at low levels on normal tissues, acting as a TRAIL decoy receptor, thus inhibiting apoptosis. DcR1 is termed a decoy receptor, as it does not have a functional death domain to induce apoptosis following TRAIL ligation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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