TotalSeq™-C1522 anti-human CD210b (IL-10RB) Antibody,BioLegend,396811
Host
Mouse
Reactivity
Human
Application
PG - Quality tested
Platform ID
BAB755328057
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C1522 anti-human CD210b (IL-10RB) Antibody
Cat. No.396811
HostMouse
RRIDAB_3717192 (BioLegend Cat. No. 396811)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberS17009F
Concentration0.5 mg/mL
TargetCD210b
ImmunogenHuman IL10RB-transfected cells
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD210b is a Type 1 transmembrane glycoprotein also known as, subunit 2 (IL-10R2) and is an essential chain for the IL-10 receptor complex. The IL-10 receptor complex is made up of alpha (IL10-RA) and beta (IL-10RB) subunits. Coexpression of these subunits has been shown to be required for IL10 induced signal transduction. Binding of dimeric IL-10 to two alpha subunits can cause the recruitment of two beta subunits resulting in the transduction of the intracellular JAK/STAT pathway.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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