TotalSeq™-C1523 anti-human CD2 Antibody, CD2, RPA-2.10,BioLegend,300245
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections6and blocking of T cell activation2. The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 300239 & 300240).
Host
Mouse
Reactivity
Human, Cynomolgus, Rhesus
Application
PG - Quality tested
Platform ID
BAB212198769
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-C1523 anti-human CD2 Antibody, CD2, RPA-2.10
Cat. No.300245
HostMouse
RRIDAB_3717166 (BioLegend Cat. No. 300245)
IsotypeMouse IgG1, κ
ReactivityHuman, Cynomolgus, Rhesus
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberRPA-2.10
Concentration0.5 mg/mL
TargetCD2
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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