TotalSeq™-D 0009 anti-human CD275 (B7-H2, ICOSL) Antibody, CD275, 2D3,BioLegend,309425

Host

Mouse

Reactivity

Human

Application

PG - Quality tested

Platform ID

BAB489633123

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameTotalSeq™-D 0009 anti-human CD275 (B7-H2, ICOSL) Antibody, CD275, 2D3
Cat. No.309425
HostMouse
RRIDAB_2936564 (BioLegend Cat. No. 309425)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone Number2D3
Concentration0.5 mg/mL
TargetCD275
ImmunogenHuman B7H2-mIg fusion protein
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-D oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

B7-H2, a member of the B7 family and the immunoglobulin superfamily, is a 40 kD protein also known as B7RP-1, B7h, B7-H2, GL50 and ICOS Ligand. Human B7-H2 is expressed by B lymphocytes, activated monocytes/macrophages, and dendritic cells. B7-H2 binds to a CD28-like receptor, inducible costimulator molecule (ICOS, AILIM, CRP-1), which is expressed by activated T cells. The interaction of ICOS with B7-H2 plays an important role in the T cell costimulation pathway.

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