Transducin-Like Enhancer Protein 1 (TLE1) Antibody,Abbexa,abx025357

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Host

Mouse

Reactivity

Human

Application

ELISA, WB

Conjugate

Unconjugated

Platform ID

BAB614064862

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameTransducin-Like Enhancer Protein 1 (TLE1) Antibody
Cat. No.abx025357
Accession NumberQ04724
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB
Working DilutionsWB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
Molecular WeightCalculated MW: 83.2 kDa
ImmunogenKLH-conjugated synthetic peptide between 199-228 amino acids from the Central region of human TLE1.
PurityPurified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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