Transient Receptor Potential Cation Channel Subfamily M Member 7 (TRPM7) Antibody,Abbexa,abx025139

TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM].

Host

Rabbit

Reactivity

Human, Mouse

Application

ELISA, WB, IHC

Conjugate

Unconjugated

Platform ID

BAB983911159

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameTransient Receptor Potential Cation Channel Subfamily M Member 7 (TRPM7) Antibody
Cat. No.abx025139
Accession NumberQ96QT4
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationELISA, WB, IHC
Working DilutionsWB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 213 kDa
ImmunogenKLH-conjugated synthetic peptide between 1821-1850 amino acids from the C-terminal region of human TRPM7 (CHAK1).
PurityPurified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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