Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) Antibody,Abbexa,abx005193
TMED10 Antibody is a Rabbit Polyclonal antibody against TMED10. This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC, IF/ICC
Conjugate
Unconjugated
Platform ID
BAB021937955
Abbexa
Contact
Tel: +44 (0) 1223 755950
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Product Specifications
Specifications
NameTransmembrane Emp24 Domain-Containing Protein 10 (TMED10) Antibody
Cat. No.abx005193
Accession NumberP49755
Gene ID (Entrez)10972
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IF/ICC
Working DilutionsELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Concentration> 0.2 mg/ml
Molecular WeightCalculated MW: 25 kDa Observed MW: 21 kDa
TargetTMED10
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10.
PurityPurified by affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Polyclonal Antibodies
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