Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) Antibody,Abbexa,abx030884

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB

Conjugate

Unconjugated

Platform ID

BAB776743061

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameTransmembrane Emp24 Domain-Containing Protein 10 (TMED10) Antibody
Cat. No.abx030884
Accession NumberP49755
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB
Working DilutionsWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 25 kDa
ImmunogenKLH-conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human TMED10.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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