TriMethyl-Histone H3-K36 Rabbit mAb- ABclonal,ABclonal,A20379

Reactivity

Human, Mouse, Rat, Other (Wide Range Predicted)

Application

WB, DB, IHC-P, IP, ELISA, ChIP, ChIP-seq

Conjugate

Unconjugated

Platform ID

BAB031740373

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTriMethyl-Histone H3-K36 Rabbit mAb- ABclonal
Cat. No.A20379
Accession NumberQ16695
Gene ID (Entrez)8290
IsotypeIgG
ReactivityHuman, Mouse, Rat, Other (Wide Range Predicted)
ConjugationUnconjugated
ApplicationWB, DB, IHC-P, IP, ELISA, ChIP, ChIP-seq
Working DilutionsWB:1:1000 - 1:6000 | DB:1:500 - 1:1000 | IHC-P:1:2000 - 1:8000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay
Clone NumberARC50050
Molecular Weight17kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Synonyms

H3.4; H3/g; H3FT; H3t; HIST3H3; Histone H3; HIST1H3A; TriMethyl-Histone H3-K36

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