TrkB (phospho Tyr515) antibody,Genetex,GTX00804

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB589552725

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTrkB (phospho Tyr515) antibody
Cat. No.GTX00804
Gene ID (Entrez)4915
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetNTRK2
ImmunogenA synthesized peptide derived from human Trk B around the phosphorylation site of Tyr516.
PurityPurified by sequential chromatography on phospho-peptide and non-phospho-peptide columnsFrom serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Synonyms

GP145TrkB , NTRK2 , TRKB , neurotrophic receptor tyrosine kinase 2 , trkB , TrkB , Trk B

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