TrkB (phospho Tyr705) antibody,Genetex,GTX78928

Host

Rabbit

Reactivity

Mouse

Application

WB

Conjugate

Unconjugated

Platform ID

BAB368480040

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameTrkB (phospho Tyr705) antibody
Cat. No.GTX78928
Gene ID (Entrez)4915
HostRabbit
IsotypeIgG
ReactivityMouse
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetNTRK2
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human TrkB around the phosphorylation site of tyrosine 705 (T-D-Y P-Y-R).
PurityPurified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.From serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format),0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Synonyms

GP145TrkB,NTRK2,TRKB,neurotrophic receptor tyrosine kinase 2,trkB,TrkB,Trk B

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