Tyrosinase antibody [T311],Genetex,GTX35154

Host

Mouse

Reactivity

Human

Application

ICC/IF IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB080984311

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTyrosinase antibody [T311]
Cat. No.GTX35154
Gene ID (Entrez)7299
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF IHC-P FCM
ClonalityMonoclonal
Concentration0.2 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTYR
ImmunogenRecombinant tyrosinase protein
PurityProtein A/G purified
Appearance/FormLiquid
FormulationPBS, 0.05% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]

Synonyms

ATN , CMM8 , OCA1 , OCA1A , OCAIA , SHEP3 , TYR , tyrosinase , Tyrosinase

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