Tyrosine Hydroxylase antibody,Genetex,GTX85470

Host

Chicken

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IHC-P IHC

Conjugate

Unconjugated

Platform ID

BAB575314505

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameTyrosine Hydroxylase antibody
Cat. No.GTX85470
Gene ID (Entrez)7054
HostChicken
IsotypeIgY
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC
ClonalityPolyclonal
Concentration200 μg/ml (Please refer to the vial label for the specific concentration.)
TargetTH
ImmunogenChickens were immunized with two synthetic peptide / keyhole limpet hemocyanin (KLH) conjugates. These synthetic peptides corresponded to different regions of the Tyrosine Hydroxylase gene product, but were shared between the human (P07101, NCBI) and mouse (P24529, NCBI) sequences.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

Synonyms

tyrosine hydroxylase , DYT14 , DYT5b , TYH

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