Tyrosine Hydroxylase antibody,Genetex,GTX113016

Host

Rabbit

Reactivity

Human, Mouse, Rat, Zebrafish, Vole, Calf

Application

WB ICC/IF IHC-P IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB629933333

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameTyrosine Hydroxylase antibody
Cat. No.GTX113016
Gene ID (Entrez)7054
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Zebrafish, Vole, Calf
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr
ClonalityPolyclonal
Concentration0.43 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTH
ImmunogenRecombinant protein encompassing a sequence within the center region of human Tyrosine Hydroxylase. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 1% BSA, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq]

Synonyms

tyrosine hydroxylase , DYT14 , DYT5b , TYH

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