U2AF65 antibody [HL1583],Genetex,GTX637062

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB086270508

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameU2AF65 antibody [HL1583]
Cat. No.GTX637062
Gene ID (Entrez)11338
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenRecombinant protein encompassing a sequence within the center region of human U2AF65. The exact sequence is proprietary.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]

Synonyms

U2 small nuclear RNA auxiliary factor 2 , U2AF65

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