UBR1 antibody,Genetex,GTX55291

Host

Rabbit

Reactivity

Human, Monkey

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB383384147

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameUBR1 antibody
Cat. No.GTX55291
Gene ID (Entrez)197131
HostRabbit
IsotypeIgG
ReactivityHuman, Monkey
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
ImmunogenKLH-conjugated synthetic peptide encompassing a sequence within the center region of UBR1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
Formulation0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol,0.01% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]

Synonyms

ubiquitin protein ligase E3 component n-recognin 1 , JBS

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