UCP1 Rabbit mAb,ABclonal,A27158

Reactivity

Mouse, Rat

Application

WB, IHC-P, IP, ELISA

Conjugate

Unconjugated

Platform ID

BAB286862913

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameUCP1 Rabbit mAb
Cat. No.A27158
Accession NumberP12242
Gene ID (Entrez)22227
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IP, ELISA
Working DilutionsWB:1:5000 - 1:50000 | IHC-P:1:500 - 1:2000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC3327
Molecular Weight33 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Enables long-chain fatty acid binding activity; oxidative phosphorylation uncoupler activity; and purine ribonucleotide binding activity. Involved in several processes, including cellular response to cold; diet induced thermogenesis; and positive regulation of cold-induced thermogenesis. Acts upstream of or within brown fat cell differentiation and regulation of transcription by RNA polymerase II. Located in mitochondrial inner membrane. Is expressed in several structures, including adipose tissue; adrenal gland; submandibular gland; testis; and thymus. Human ortholog(s) of this gene implicated in hypertension and type 2 diabetes mellitus. Orthologous to human UCP1 (uncoupling protein 1).

Synonyms

Ucp; Slc25a7

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