ULBP1 antibody [10K10],Genetex,GTX53047

Host

Mouse

Reactivity

Human

Application

FCM Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB061782268

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameULBP1 antibody [10K10]
Cat. No.GTX53047
Gene ID (Entrez)80329
HostMouse
IsotypeIgG2
ReactivityHuman
ConjugationUnconjugated
ApplicationFCM Neutralizing /Inhibition
ClonalityMonoclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenHuman recombinant ULBP-1
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Synonyms

N2DL1 , NKG2DL1 , RAET1I , UL16 binding protein 1 , ULBP1

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