ULK3 Recombinant Antibody,Bioss,bsm-61618r-TR

Host

Rabbit

Reactivity

Human

Application

WB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC)

Conjugate

Unconjugated

Platform ID

BAB432768936

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameULK3 Recombinant Antibody
Cat. No.bsm-61618r-TR
Accession NumberQ6PHR2
Gene ID (Entrez)25989
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:500-2000 | FCM:FCM1:50-100 | IHC-P:IHC-P1:50-200 | IHC-F:IHC-F1:50-200 | IF(IHC-P):IFIHC-P1:50-200 | IF(ICC):IFICC1:50-200
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation.

Synonyms

Serine/threonine-protein kinase ULK3; Ulk3; unc 51 like kinase 3 (C. elegans); Unc-51-like kinase 3.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.