Ube2J2 antibody,Genetex,GTX48692

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IP ELISA

Conjugate

Unconjugated

Platform ID

BAB488156361

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameUbe2J2 antibody
Cat. No.GTX48692
Gene ID (Entrez)118424
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IP ELISA
ClonalityPolyclonal
Concentration0.91 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenSynthetic peptide corresponding to an internal region of the human Ube2j2 protein.
PurityPurified by antigen-affinity chromatography.From serum
Appearance/FormLiquid
Formulation20mM Potassium Phosphate, 150mM NaCl,0.01% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Ube2j2 and Ube2j1 are homologs of the yeast ubiquitin-conjugating enzyme UBC6, which catalyzes the covalent attachment of ubiquitin to other proteins. These proteins constitute a distinct family of ubiquitin-conjugating enzymes sharing a conserved non-canonical active site sequence and a C-terminal trans-membrane domain. By analogy with yeast UBC6, Ube2j1 and Ube2j2 are localized to the endoplasmic reticulum and seem to function in the selective degradation of misfolded membrane proteins and in general mediation of the stress response.

Synonyms

ubiquitin conjugating enzyme E2 J2 , NCUBE-2 , NCUBE2 , PRO2121

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