Ultra-LEAF™ Purified anti-human CD178 (FasL) Antibody, CD178, W19403O,BioLegend,949104
Host
Mouse
Reactivity
Human
Application
Neut - Quality tested
Platform ID
BAB584276408
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameUltra-LEAF™ Purified anti-human CD178 (FasL) Antibody, CD178, W19403O
Cat. No.949104
HostMouse
RRIDAB_2936681 (BioLegend Cat. No. 949103)AB_2936681 (BioLegend Cat. No. 949104)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationNeut - Quality tested
ClonalityMonoclonal
Clone NumberW19403O
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetCD178
ImmunogenRecombinant human FASL (TNFSF6)
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
FASL was initially cloned and purified from a cytotoxic T cell hybridoma, PC60-d10S. FASL is a type II transmembrane glycoprotein of approximately 40 kD and belongs to the TNF family of membrane-associated cytokines. A soluble fragment of FASL (sFASL, 26-29 kD) has been described using in vitro proteolytic assays, and MMP7 was proposed to participate in this process. Nevertheless, TIMPs (tissue inhibitors of metalloproteinases) did not alter FASL shedding.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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