Ultra-LEAF™ Purified anti-human CD2 Antibody, CD2, TS1/8,BioLegend,309235
Additional reported applications (for the relevant formats) include: blocking of T cell activation, and partial blocking of B cell costimulation2. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 309235 & 309236).
Host
Mouse
Reactivity
Human
Application
FC -Quality testedBlock -Reported in the literature, not verified in house
Platform ID
BAB220994545
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameUltra-LEAF™ Purified anti-human CD2 Antibody, CD2, TS1/8
Cat. No.309235
HostMouse
RRIDAB_2860824 (BioLegend Cat. No. 309235)AB_2860825 (BioLegend Cat. No. 309236)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality testedBlock -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberTS1/8
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetCD2
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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