Ultra-LEAF™ Purified anti-human CD337 (NKp30) Antibody, CD337, W20238A,BioLegend,380606

CD337, also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3, is recognized by the W20238A monoclonal antibody. CD337, a member of the natural cytotoxicity receptor family is a type I transmembrane protein with one immunoglobulin-like domain and a molecular weight of 30 kD. It exists in six isoforms from alternative splicing. NKp30 is expressed on resting and activated NK cells and enhances NK cell cytolysis of tumor cells that are deficient in MHC class I molecules. CD337 is involved in activating and expanding resting NK cells following interaction with dendritic cells to eliminate tumor, virus-infected, and immature dendritic cells.