Ultra-LEAF Purified anti-human HLA-DR Antibody anti-HLA-DR - L243,BioLegend,307648
The L243 monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. Clone L243 binds a conformational epitope on HLA-DRa which depends on the correct folding of the aß heterodimer.19Additional reported applications (for the relevant formats) include: immunoprecipitation8, Western blotting8,in vitroblocking of mixed lymphocyte reactions9,10, depeletion of MHC class II cells7, immunohistochemical staining of acetone-fixed frozen sections4,5, and spatial biology (IBEX)21,22. For sensitive functional assays, we recommend using the Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 307648, 307665 - 307669).
Host
Mouse
Reactivity
Human, Cynomolgus, Rhesus
Application
FC -Quality testedCyTOF® -VerifiedIP, WB, Block, IHC-F -Reported in the literature, not verified in house
Platform ID
BAB618982270
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameUltra-LEAF Purified anti-human HLA-DR Antibody anti-HLA-DR - L243
Cat. No.307648
HostMouse
RRIDAB_2800796 (BioLegend Cat. No. 307665)AB_2561493 (BioLegend Cat. No. 307648)AB_2800797 (BioLegend Cat. No. 307666)AB_2800798 (BioLegend Cat. No. 307667)AB_2800799 (BioLegend Cat. No. 307668)AB_2800800 (BioLegend Cat. No. 307669)
IsotypeMouse IgG2a, κ
ReactivityHuman, Cynomolgus, Rhesus
ApplicationFC -Quality testedCyTOF® -VerifiedIP, WB, Block, IHC-F -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberL243
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetHLA-DR
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
This product is eligible for a 40% discount!To take advantage of this offer,please contact your local representative. This promotion is valid through April 30th. Exclusions apply. To view full promotion terms and conditions, visit ourPromotions page.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.