Ultra-LEAF™ Purified anti-human TNF-α (Adalimumab Biosimilar) Recombinant Antibody, TNF-α, QA23A57,BioLegend,648827
Host
Human
Reactivity
Human
Application
Neut - Quality tested
Platform ID
BAB628166595
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameUltra-LEAF™ Purified anti-human TNF-α (Adalimumab Biosimilar) Recombinant Antibody, TNF-α, QA23A57
Cat. No.648827
HostHuman
RRIDAB_3720532 (BioLegend Cat. No. 648826)AB_3720532 (BioLegend Cat. No. 648827)
IsotypeHuman IgG1, κ
ReactivityHuman
ApplicationNeut - Quality tested
ClonalityRecombinant
Clone NumberQA23A57
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetTNF-alpha
ImmunogenRecombinant human TNF-α
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in 150 mM NaCl, pH 6.5, containing no preservative
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
TNF-α is released from macrophages, monocytes, neutrophils, T-cells (principally CD4+), NK-cells and many transformed cell lines. Soluble homotrimer TNF-α is released from cells by proteolysis of the integral membrane precursor form of TNF-α. Binding of TNF-α to some of its receptors induces apoptosis. Depending on cell types, receptor expression, and signal transduction status, this binding may induce other responses. In addition, TNF-α is involved in a wide range of pro-inflammatory response.
Category Paths
- Products>Primary Antibodies>Recombinant Antibodies
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