Ultra-LEAF™ Purified anti-human/mouse/rat CD278 (ICOS) Recombinant Antibody, CD278, QA17A11,BioLegend,395203
Host
Human
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB205601937
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameUltra-LEAF™ Purified anti-human/mouse/rat CD278 (ICOS) Recombinant Antibody, CD278, QA17A11
Cat. No.395203
HostHuman
RRIDAB_2783311 (BioLegend Cat. No. 395203)AB_2783312 (BioLegend Cat. No. 395204)
IsotypeHuman IgG4, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityRecombinant
Clone NumberQA17A11
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetCD278
ImmunogenMouse T cell clone D10.G4.1
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
CD278, also know as ICOS, is a type I transmembrane protein, member of the CD28/CTLA-4 family, present in the cell surface as an homodimer of 47-57 kD. ICOS is expressed in activated T cells where it has a pivotal role in T cell activation, proliferation and Th1/Th2 differentiation and the antibody response; its ligand is CD275.
Category Paths
- Products>Primary Antibodies>Recombinant Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.