Ultra-LEAF™ Purified anti-mouse 4-1BB Ligand (CD137L) Antibody, CD137L, TKS-1,BioLegend,107116
The TKS-1 antibody inhibits binding of soluble 4-1BB to 4-1BBLin vitro. Additional reported applications (for the relevant formats) include:in vitroblocking the binding of 4-1BB to 4-1BBL1. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 107106) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 107104) followed by SAv-PE (Cat. No. 405204)). The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 107111-107116).
Host
Rat
Reactivity
Mouse
Application
FC -Quality testedBlock -Reported in the literature, not verified in house
Platform ID
BAB094732651
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameUltra-LEAF™ Purified anti-mouse 4-1BB Ligand (CD137L) Antibody, CD137L, TKS-1
Cat. No.107116
HostRat
RRIDAB_2832355 (BioLegend Cat. No. 107111)AB_2832356 (BioLegend Cat. No. 107112)AB_2832357 (BioLegend Cat. No. 107113)AB_2832358 (BioLegend Cat. No. 107114)AB_2832359 (BioLegend Cat. No. 107115)AB_2894664 (BioLegend Cat. No. 107116)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality testedBlock -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberTKS-1
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetCD137L
ImmunogenBALB/c mouse B lymphoma line 2PK-3
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
4-1BB ligand, also known as CD137L, is a 97 kD member of the TNF superfamily present on antigen-presenting cells (dendritic cells and macrophages) and activated B and T lymphocytes. 4-1BBL interacts with 4-1BB (CD137) to induce T and B cell costimulation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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