Ultra-LEAF™ Purified anti-mouse CD252 (OX40 Ligand) Antibody, CD252, RM134L,BioLegend,108819
The RM134L antibody can block the costimulatory activity of OX40L. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections3, andin vivoandin vitroblocking of OX-40L-OX-40 functional interaction1,2,4. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 108808).
Host
Rat
Reactivity
Mouse
Application
FC -Quality testedIHC-F -Reported in the literature, not verified in house
Platform ID
BAB022755952
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameUltra-LEAF™ Purified anti-mouse CD252 (OX40 Ligand) Antibody, CD252, RM134L
Cat. No.108819
HostRat
RRIDAB_2860619 (BioLegend Cat. No. 108819)AB_2860620 (BioLegend Cat. No. 108820)AB_2860621 (BioLegend Cat. No. 108821)AB_2860622 (BioLegend Cat. No. 108822)AB_2860623 (BioLegend Cat. No. 108823)AB_2860624 (BioLegend Cat. No. 108824)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC -Quality testedIHC-F -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberRM134L
ConcentrationThe antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.
TargetCD252
ImmunogenRat NRK-52E cell line transfected with mouse OX-40L
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
CD252 is a 35 kD member of the TNF superfamily and is also known as OX40 ligand, OX40L, and CD134L. The CD252 is expressed on activated B cells and antigen presenting cells. CD252 interacts with OX40 antigen (CD134), expressed predominantly on activated T cells to increase proliferation and IL-2 production and to enhance proliferation and immunoglobulin secretion in activated B cells.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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